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Louis M Havekes Selected Research

CNTO 736

1/2009CNTO736, a novel glucagon-like peptide-1 receptor agonist, ameliorates insulin resistance and inhibits very low-density lipoprotein production in high-fat-fed mice.

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Louis M Havekes Research Topics

Disease

35Atherosclerosis
11/2015 - 04/2002
27Insulin Resistance
11/2015 - 06/2002
16Hypertriglyceridemia
08/2013 - 09/2002
14Obesity
03/2015 - 06/2002
13Body Weight (Weight, Body)
11/2015 - 08/2003
12Hyperlipidemias (Hyperlipidemia)
01/2013 - 02/2002
11Inflammation (Inflammations)
11/2015 - 07/2003
7Dyslipidemias (Dyslipidemia)
11/2015 - 08/2003
7Cardiovascular Diseases (Cardiovascular Disease)
10/2013 - 06/2004
6Type 2 Diabetes Mellitus (MODY)
11/2015 - 05/2005
6Hypercholesterolemia
01/2012 - 08/2003
5Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2015 - 06/2004
5Hyperlipoproteinemia Type III (Broad Beta Disease)
01/2013 - 02/2002
5Atherosclerotic Plaque (Atheroma)
01/2013 - 04/2002
4Sepsis (Septicemia)
05/2008 - 01/2005
3Weight Gain
11/2015 - 01/2013
3Fatty Liver
05/2014 - 04/2004
3Neointima
02/2010 - 01/2007
2Weight Loss (Weight Reduction)
12/2014 - 01/2012
2Hyperglycemia
05/2013 - 01/2013
2Hepatocellular Carcinoma (Hepatoma)
01/2013 - 09/2002
2Glucose Intolerance
01/2012 - 01/2008
2Hypertension (High Blood Pressure)
01/2012 - 01/2011
2Alzheimer Disease (Alzheimer's Disease)
04/2008 - 11/2007
2Infections
02/2008 - 08/2003
2Rupture
12/2005 - 04/2002
2Coinfection
02/2005 - 08/2003
2Hyperinsulinism (Hyperinsulinemia)
10/2004 - 02/2002
2Protein Deficiency
05/2004 - 05/2003
1Fibrosis (Cirrhosis)
11/2015
1Alcoholic Fatty Liver
11/2015
1Hypertrophy
05/2014
1Cushing Syndrome
10/2013
1Chronic Obstructive Pulmonary Disease (COPD)
01/2013

Drug/Important Bio-Agent (IBA)

47Apolipoproteins E (ApoE)IBA
11/2015 - 09/2002
30CholesterolIBA
03/2015 - 05/2002
25Triglycerides (Triacylglycerol)IBA
03/2015 - 08/2003
25Glucose (Dextrose)FDA LinkGeneric
03/2014 - 06/2002
18Insulin (Novolin)FDA Link
04/2014 - 06/2002
18LipidsIBA
05/2013 - 05/2002
18ApolipoproteinsIBA
02/2010 - 04/2002
12Fatty Acids (Saturated Fatty Acids)IBA
03/2015 - 01/2004
11Lipoproteins (Lipoprotein)IBA
03/2015 - 09/2002
9Lipoprotein Lipase (Diacylglycerol Lipase)IBA
12/2009 - 08/2003
8Apolipoprotein C-I (Apolipoprotein C1)IBA
05/2008 - 01/2004
6Atorvastatin (Lipitor)FDA Link
01/2015 - 09/2002
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2008 - 09/2003
5Cholesterol Ester Transfer ProteinsIBA
11/2015 - 11/2006
5HDL CholesterolIBA
11/2015 - 05/2008
5LipopolysaccharidesIBA
05/2014 - 10/2006
5CytokinesIBA
08/2010 - 04/2005
5Apolipoprotein E2IBA
05/2009 - 02/2002
4Nonesterified Fatty Acids (NEFA)IBA
04/2014 - 08/2003
4Apolipoprotein E3IBA
01/2011 - 02/2003
4VLDL LipoproteinsIBA
05/2009 - 09/2005
4HDL LipoproteinsIBA
05/2009 - 10/2006
4Apolipoproteins C (ApoC)IBA
04/2008 - 02/2005
4LDL Receptors (LDL Receptor)IBA
05/2004 - 05/2002
3oxidized low density lipoproteinIBA
11/2015 - 01/2005
3Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
08/2013 - 09/2003
3Proteins (Proteins, Gene)FDA Link
01/2013 - 11/2003
3Rosiglitazone (Avandia)FDA Link
01/2013 - 08/2003
3very low density lipoprotein triglycerideIBA
12/2011 - 07/2005
3Apolipoprotein C-IIIIBA
05/2008 - 07/2005
3Apolipoprotein E4IBA
04/2008 - 02/2003
3Serum Amyloid A Protein (Serum Amyloid A)IBA
08/2006 - 09/2003
2anacetrapibIBA
11/2015 - 01/2015
2LDL CholesterolIBA
11/2015 - 06/2010
2Niacin (Nicotinic Acid)FDA LinkGeneric
04/2014 - 01/2013
2GlucocorticoidsIBA
10/2013 - 01/2013
2Blood Glucose (Blood Sugar)IBA
05/2013 - 11/2005
2CorticosteroneIBA
01/2013 - 08/2012
2Phosphotransferases (Kinase)IBA
02/2012 - 05/2011
2RimonabantIBA
01/2012 - 01/2011
2Ritonavir (Norvir)FDA Link
06/2010 - 01/2006
2HIV Protease InhibitorsIBA
06/2010 - 01/2006
2baysilon (polydimethylsiloxane)IBA
12/2005 - 04/2002
2Messenger RNA (mRNA)IBA
12/2005 - 03/2005
2Fish OilsIBA
05/2005 - 11/2003
2Amlodipine (Norvasc)FDA LinkGeneric
07/2003 - 09/2002
1salicylsalicylic acid (salsalate)IBA
11/2015
1CannabinoidsIBA
12/2014
1MelanocortinsIBA
10/2014
1Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA
10/2014
1CarbohydratesIBA
05/2014
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
05/2014
1Transcription Factors (Transcription Factor)IBA
05/2014
1Peroxidase (Myeloperoxidase)IBA
05/2014
1InterleukinsIBA
05/2014
1Adrenergic Agents (Adrenergic Drugs)IBA
04/2014
1Type 3 Cyclic Nucleotide PhosphodiesterasesIBA
04/2014
1Metformin (Glucophage)FDA LinkGeneric
03/2014
1ResveratrolIBA
08/2013
1Apolipoprotein A-VIBA
08/2013
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
06/2013
1Bile Acids and Salts (Bile Acids)IBA
05/2013
1cholebine (colestilan)IBA
05/2013
1Pancreatic Elastase (Elastase)IBA
01/2013

Therapy/Procedure

6Therapeutics
08/2013 - 04/2002
2Fat-Restricted Diet (Diet, Fat Restricted)
01/2013 - 06/2002